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Thursday 30 December 2010
Just2Pure RTI-126 Methoxetamine Benzo Fury IN STOCK NOW
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Methoxetamine
Methoxetamine is a chemical of the arylcyclohexylamine class. It is an analogue of ketamine that also contains structural features of tiletamine and 3-MeO-PCP. The 2-chloro group on the phenyl ring and the N-methyl group on the amine have been replaced by 3-methoxy and N-ethyl groups, respectively.[1]
RTI-126 Information
RTI-126, ((-)-2β-(1,2,4-oxadiazol-5-methyl)-3β-phenyltropane) is a phenyltropane derivative which acts as a potent monoamine reuptake inhibitor and stimulant drug. It is around 5x more potent a stimulant than cocaine, but is relatively unselective, binding to all three monoamine transporters although still with some selectivity for the dopamine transporter.[1] RTI-126 has a fast onset of effects and short duration of action, and its pharmacological profile in animals is among the closest to cocaine itself out of all the drugs in the RTI series. Its main application in scientific research has been in studies investigating the influence of pharmacokinetics on the abuse potential of stimulant drugs, with its rapid entry into the brain thought to be a key factor in producing its high propensity for development of dependence in animals.[2][3]
RTI-126 is not explicitly illegal anywhere in the world; its similar pharmacological activity to cocaine makes it possible that it could be considered a controlled substance analogue in countries such as the USA, Canada, Australia and New Zealand which have controlled substance analogue legislation,[citation needed] but the replacement of the 2β-carbomethoxy group with methyloxadiazole is a significant[citation needed] structural alteration and it is unclear whether it could be considered "substantially similar" in chemical structure so as to bring it within the definition of a controlled substance analogue.[citation needed] There is as yet no case law defining what constitutes a substantially similar chemical structure, and so it is not possible to say for certain whether RTI-126 would be an illegal drug or not.[citation needed]
It is interesting to note that the structurally related compound (-)-2β-(3-methyl-5-isoxazolyl)nortropane is a potent and selective agonist for nicotinic acetylcholine receptors, with twice the potency of nicotine.[4]
RTI-126 is not explicitly illegal anywhere in the world; its similar pharmacological activity to cocaine makes it possible that it could be considered a controlled substance analogue in countries such as the USA, Canada, Australia and New Zealand which have controlled substance analogue legislation,[citation needed] but the replacement of the 2β-carbomethoxy group with methyloxadiazole is a significant[citation needed] structural alteration and it is unclear whether it could be considered "substantially similar" in chemical structure so as to bring it within the definition of a controlled substance analogue.[citation needed] There is as yet no case law defining what constitutes a substantially similar chemical structure, and so it is not possible to say for certain whether RTI-126 would be an illegal drug or not.[citation needed]
It is interesting to note that the structurally related compound (-)-2β-(3-methyl-5-isoxazolyl)nortropane is a potent and selective agonist for nicotinic acetylcholine receptors, with twice the potency of nicotine.[4]
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